GHK-Cu and collagen synthesis in fibroblast cultures (1988)
Fibroblast cultures showed greater collagen synthesis after exposure to GHK-Cu, independently of changes in cell number. The experiment did not test a clinical skin outcome.
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GHK-Cu is a copper complex of the tripeptide glycyl-histidyl-lysine, investigated in laboratory studies of collagen and skin biology.
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GHK consists of three amino acids and can bind copper(II) ions to form GHK-Cu. Research has examined how this complex affects fibroblasts, the cells that produce connective-tissue components. A foundational culture study reported increased collagen synthesis without an increase in cell number. A later investigation compared GHK-Cu, hyaluronic acid and their combinations in fibroblasts and skin explants. Some combinations increased collagen IV measures more than either component alone. These experiments describe cellular and isolated-tissue responses; they did not measure wrinkle reduction or wound recovery in treated people.
Each source identifies what was studied and the limits of its findings. Published research is separate from this product’s batch COA.
Fibroblast cultures showed greater collagen synthesis after exposure to GHK-Cu, independently of changes in cell number. The experiment did not test a clinical skin outcome.
Read studyCertain GHK-Cu–hyaluronic acid combinations increased collagen IV measures in fibroblasts and skin explants. The findings concern experimental mixtures and do not establish cosmetic effectiveness in people.
Read studyGHK-Cu is currently listed in 50 mg, 100 mg. Select a strength above to see its price, product image and current stock. Listed quantities are supplied specifications, not measured batch results.
1 laboratory report is published for this compound. Match the selected strength and available batch identifiers, and open the original document to check the actual test scope.
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